diff --git a/contrib/gitian-descriptors/gitian-osx.yml b/contrib/gitian-descriptors/gitian-osx.yml
index f3b0346c5..31259de25 100644
--- a/contrib/gitian-descriptors/gitian-osx.yml
+++ b/contrib/gitian-descriptors/gitian-osx.yml
@@ -23,9 +23,9 @@ packages:
 - "libcap-dev"
 - "libz-dev"
 - "libbz2-dev"
-- "python"
-- "python-dev"
-- "python-setuptools"
+- "python3"
+- "python3-dev"
+- "python3-setuptools"
 - "fonts-tuffy"
 remotes:
 - "url": "https://github.com/dogecoin/dogecoin.git"
diff --git a/depends/packages/native_biplist.mk b/depends/packages/native_biplist.mk
index 3c6e8900f..373490aed 100644
--- a/depends/packages/native_biplist.mk
+++ b/depends/packages/native_biplist.mk
@@ -11,10 +11,10 @@ define $(package)_preprocess_cmds
 endef
 
 define $(package)_build_cmds
-    python setup.py build
+    python3 setup.py build
 endef
 
 define $(package)_stage_cmds
     mkdir -p $($(package)_install_libdir) && \
-    python setup.py install --root=$($(package)_staging_dir) --prefix=$(build_prefix) --install-lib=$($(package)_install_libdir)
+    python3 setup.py install --root=$($(package)_staging_dir) --prefix=$(build_prefix) --install-lib=$($(package)_install_libdir)
 endef
diff --git a/depends/packages/native_ds_store.mk b/depends/packages/native_ds_store.mk
index 1053a0cd3..671c68bbc 100644
--- a/depends/packages/native_ds_store.mk
+++ b/depends/packages/native_ds_store.mk
@@ -7,10 +7,10 @@ $(package)_install_libdir=$(build_prefix)/lib/python/dist-packages
 $(package)_dependencies=native_biplist
 
 define $(package)_build_cmds
-    python setup.py build
+    python3 setup.py build
 endef
 
 define $(package)_stage_cmds
     mkdir -p $($(package)_install_libdir) && \
-    python setup.py install --root=$($(package)_staging_dir) --prefix=$(build_prefix) --install-lib=$($(package)_install_libdir)
+    python3 setup.py install --root=$($(package)_staging_dir) --prefix=$(build_prefix) --install-lib=$($(package)_install_libdir)
 endef
diff --git a/depends/packages/native_mac_alias.mk b/depends/packages/native_mac_alias.mk
index 8dc283143..3b0e6852a 100644
--- a/depends/packages/native_mac_alias.mk
+++ b/depends/packages/native_mac_alias.mk
@@ -12,10 +12,10 @@ define $(package)_preprocess_cmds
 endef
 
 define $(package)_build_cmds
-    python setup.py build
+    python3 setup.py build
 endef
 
 define $(package)_stage_cmds
     mkdir -p $($(package)_install_libdir) && \
-    python setup.py install --root=$($(package)_staging_dir) --prefix=$(build_prefix) --install-lib=$($(package)_install_libdir)
+    python3 setup.py install --root=$($(package)_staging_dir) --prefix=$(build_prefix) --install-lib=$($(package)_install_libdir)
 endef